By: Julia Aidan
Submitted: 2010-02-12 10:42:30 | Word Count: 378
The biotechnology in medical science is called biopharmaceuticals. These are amalgamation of proteins (which includes anti-bodies), nucleic acids (DNA, RNA or antisense oligonucleotides) used for diagnostics purposes in living organisms.
Genentech Inc developed the product. Nontheless, it was licensed to a global pharmaceutical company called Eli Lilly and Company, under which the manufacturing and marketing begun in 1982.
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CATEGORISATION OF BIOPHARMACEUTICAL
Biopharmaceutical classified as Blood factors, Interferons, Vaccines, Monoclonal antibodies, Haematopoietic growth factors, Hormones and Thrombolytic agents..
USES OF BIOPHARMACEUTICAL
Biopharmaceuticals are used for treatment of variety ailments like anemia, leukemia, rheumatoid arthritis, neutropenia, Gaucher's disease, multiple sclerosis, etc.
PROTEIN MANUFACTURING
The drugs are very complicated and takes time. It takes a number of years only to identify the sanative protein, gene sequence and validation process for producing of molecules applying biotechnology. This has helped in producing the chemicals in a cost effective method.
The combination of certain white blood cells with tumor cells is called Hybridomas. Cancer and other vital disorders are effectively treated by these drugs.
RDNA or genetic engineering, has let the gene that allows for the necessitate protein and need to be transferred from one living being to another, so that, huge quantity of drugs can be made. In the process, the transformed host cell that contains the required gene are developed in controlled conditions in large stainless-steel tanks. The cells are then aroused to make the necessary proteins by certain conditions like maintaining a desirable balance of acidity, temperature and oxygen among other entities. The proteins are subject to rigorous quality test.
Like every things having their advantages and disadvantages, protein manufacturing has also its very own advantages and disadvantages.
ADVANTAGES OF PROTEIN MANUFACTURING
The cells of micro-organisms like yeast, bacteria, algae which are used as a source in PROTEIN MANUFACTURING, produces very huge quantity of protein in 24 hrs. For example, 50 lbs of yeast can create 125 tons of proteins in a day.
Bacteria have very quick growth rate with very high in protein.
DISADVANTAGES OF PROTEIN MANUFACTURING
Harvesting bacterial cells are very costly and difficult.
Nucleic acid can be fatal for human beings. Level of nucleic acid can be decreased through added processing step, and thus increasing the cost of manufacturing.
Author Resource:-
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